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Genome-wide CRISPR screen identifies non-canonical NF-κB signaling as a regulator of density-dependent proliferation
Maria Fomicheva, Ian G Macara
A novel checkpoint pathway controls actomyosin ring constriction trigger in fission yeast
Tomás Edreira et al.
In fission yeast cell wall stress triggers a cytokinesis blockage specifically in the onset of actomyosin ring constriction.
Dot1l interacts with Zc3h10 to activate Ucp1 and other thermogenic genes
Danielle Yi et al.
Dot1l and its H3K79 methyltransferase activity are required for thermogenesis, and Dot1l is recruited by Zc3h10 to its targets genes to alter chromatin accessibility to activate the thermogenic gene program.
Coordinated crosstalk between microtubules and actin by a spectraplakin regulates lumen formation and branching
Delia Ricolo, Sofia J Araujo
Lumen formation by single epithelial cells depends on FGF-signalling-dependent expression of a spectraplakin, which can be functionally replaced by Tau.
Biochemistry and Chemical Biology
Synergy between Wsp1 and Dip1 may initiate assembly of endocytic actin networks
Connor John Balzer et al.
BLOS1 mediates kinesin switch during endosomal recycling of LDL receptor
Chang Zhang et al.
A versatile Oblique Plane Microscope for large-scale and high-resolution imaging of subcellular dynamics
Etai Sapoznik et al.
nucleates a transcription inhibitory complex to balance neuronal differentiation
Anne Kruse Hollensen et al.
A neuron-specific circular RNA keeps neuronal differentiation in check by lowering transcription rates from key neuronal marker genes.
Optimized Vivid-derived Magnets photodimerizers for subcellular optogenetics in mammalian cells
Lorena Benedetti et al.
Chromosomes and Gene Expression
Alpha-satellite RNA transcripts are repressed by centromere-nucleolus associations
Leah Bury et al.
Imaging methods are vastly underreported
Guillermo Marqués et al.
Philosophy of Biology: Knowledge and illusions
Antony M Jose
A role for fat cells in bone marrow
Utrecht University, Netherlands
Marianne E Bronner
California Institute of Technology, United States
University of Sydney, Australia
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