Editors for Biochemistry and Chemical Biology
Senior editors
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Philip Cole
Harvard Medical School, United States
Phil Cole is Professor of Medicine and Biological Chemistry and Molecular Pharmacology at Harvard Medical School and is a Senior Investigator in the Division of Genetics at Brigham and Women's Hospital. He graduated from Yale University with a B.S. in Chemistry and then spent a year as a Churchill Scholar at the University of Cambridge prior to obtaining M.D. and Ph.D. degrees from Johns Hopkins School of Medicine where he pursued research in bioorganic chemistry. Cole then entered post-doctoral and clinical training at Harvard Medical School and Brigham and Women's Hospital. He subsequently held faculty positions at Rockefeller University and then Johns Hopkins where he was Chair of Pharmacology prior to returning to Harvard in 2017. His research interests are related to the chemical biology of cell signaling and epigenetics. His group has developed and applied methods for protein semisynthesis and small molecule probes for kinases, acyltransferases, deacetylases, and demethylases. His honors include election to the ASCI, fellow of the AAAS, and receipt of an NIH MERIT award.
- Expertise
- Biochemistry and Chemical Biology
- Research focus
- chemical biology
- cell signalling
- epigenetics
- post-translational modifications
- enzymology
- Competing interests statement
- Philip Cole is on the Scientific Advisory Boards of Memorial Sloan-Kettering Cancer Center, the Maryland Institute of Bioscience and Biotechnology Research, and the Searle Scholars Program. He is a cofounder of Acylin Therapeutics Inc and a science advisor for the Abbvie, Epizyme, and Forma companies and has been a consultant for MPM Capital. Cole has received research funding from the NIH, the FAMRI foundation, and the V Foundation. He is a member of the editorial boards of the following journals: J Biol Chem, Biomed Central Biology, ChemBioChem, and Bioorganic Chemistry.
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José Faraldo-Gómez
National Heart, Lung and Blood Institute, National Institutes of Health, United States
José Faraldo-Gómez studied Physics at the Universidad Autónoma in Madrid, Spain, and went on to pursue a PhD degree in the Laboratory of Molecular Biophysics at the University of Oxford, graduating in 2002. He then moved to the United States, and acquired postdoctoral training first at the Weill Medical College of Cornell University in New York City, and subsequently at the University of Chicago. His pre- and post-doctoral work was focused on membrane proteins and in later years also on signaling enzymes, studied through computer simulations and other theoretical methods. In late 2007, Dr Faraldo-Gómez established the Theoretical Molecular Biophysics Laboratory at the Max Planck Institute of Biophysics in Frankfurt, Germany. In 2013, Dr Faraldo-Gómez relocated his laboratory to the National Institutes of Health, in Bethesda, MD, USA, where he joined the National Heart, Lung and Blood Institute as a Tenure-Track Investigator. He became a tenured Senior Investigator in 2016. Dr Faraldo-Gómez served as a handling editor at the Biophysical Journal from 2011 to 2017, and as an Associate Editor in the Journal of General Physiology from 2016 to 2019. At eLife, he first served as a Reviewing Editor, from 2017 to 2019, and is now a Senior Editor.
- Expertise
- Biochemistry and Chemical Biology
- Structural Biology and Molecular Biophysics
- Research focus
- computational biophysics
- molecular computation
- membrane protein
- Competing interests statement
- José Faraldo-Gómez has no competing interests to disclose. Dr Faraldo-Gómez is a Senior Investigator at the National Heart, Lung and Blood Institute of the US National Institutes of Health.
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David James
University of Sydney, Australia
Professor James currently holds the Leonard P Ullmann Chair in Molecular Systems Biology and he is the Domain Leader for Biology at the Charles Perkins Centre, University of Sydney. Professor James has made major contributions to our understanding of insulin action. In the late 1980s he published a series of journal articles in Nature describing the identification and characterization of the insulin responsive glucose transporter GLUT4. Professor James then focused his efforts on unveiling the cellular and molecular control of insulin-stimulated glucose transport. He has also made contributions in the area of SNARE proteins, signal transduction and more recently in systems biology.
- Expertise
- Cell Biology
- Biochemistry and Chemical Biology
- Research focus
- diabetes
- metabolism
- insulin action
- protein phosphorylation
- signal transduction
- Experimental organism
- D. melanogaster
- human
- mouse
- Competing interests statement
- David James has been funded by bodies like National Health and Medical Research Council (NHMRC), Wellcome Trust, Australian Research Council (ARC), NIH, Pfizer, Eli Lilly and Novo, had continuous NHMRC research fellowships since 1998 and is now Senior Principal Research Fellow.
James has served on editorial boards of journals such as The Journal of Biological Chemistry and The American Journal of Physiology for more than 10 years and is currently on five boards with major roles at Cell Metabolism (only Australian) and The Journal of Clinical Investigation. James reviews ~30 manuscripts per year for journals like Nature, Nature Cell Biology, Nature Medicine, Science, PNAS, The Journal Clinical Invest, Molecular Endocrinology, Endocrinology, Molecular Biology of the Cell, Journal of Cell Biology, Traffic, FASEB J, Genes & Development and grants for Diabetes Australia, National Heart, Wellcome Trust, ARC, NHMRC and International Foundations.
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John Kuriyan
University of California, Berkeley, United States
John Kuriyan is Professor of Molecular and Cell Biology and also of Chemistry at the University of California, Berkeley. Before this, he was on the faculty at The Rockefeller University, New York, where he began his career in 1987, leaving for Berkeley in 2001. Since 1990, he has been an Investigator of the Howard Hughes Medical Institute. Kuriyan completed undergraduate studies in chemistry at Juniata College, Huntingdon, PA. His doctoral research, on the dynamics of proteins, was carried out at MIT, under the guidance of Greg Petsko and Martin Karplus (Harvard University). Kuriyan’s research is aimed at understanding the structure and mechanism of the enzymes and molecular switches that carry out cellular signal transduction and DNA replication. His laboratory uses x-ray crystallography to determine the three-dimensional structures of proteins involved in signaling and replication, as well as biochemical, biophysical, and computational analyses to elucidate mechanisms. Kuriyan was elected to the US National Academy of Sciences in 2001.
- Expertise
- Biochemistry and Chemical Biology
- Structural Biology and Molecular Biophysics
- Research focus
- protein science and biochemistry
- signaling
- crystallography
- electron microscopy
- modeling
- molecular dynamics
- Competing interests statement
- John Kuriyan has received funding from the Howard Hughes Medical Institute, the US National Institutes of Health, and the Leukemia and Lymphoma Society. He serves on the editorial board of the Proceedings of the National Academy of Sciences, and on the Scientific Advisory Boards of Carmot Therapeutics (San Francisco) and Jubilant Biosys (Bangalore). He is a founder of Nurix (San Francisco).
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Vivek Malhotra
The Barcelona Institute of Science and Technology, Spain
Vivek Malhotra was a professor in the biology division at UC San Diego from 2007 and is now the ICREA Professor and Chair of the Cell and Developmental Biology at Center for Genomic Regulation (CRG) in Barcelona. His research focuses on a central station of the secretory pathway, the Golgi complex. Specifically, his work has resulted in the identification of the machinery required for the sorting and packaging of secretory cargoes. His recent work has uncovered a novel secretory routing that bypasses the conventional pathway of protein secretion. He has identified new genes required for the export of bulky collagens and the regulated secretion of mucins. He received his BSc from Stirling University and was a Pirie–Reid scholar at Oxford, a Damon Runyon Walter Winchell and an American Cancer Society postdoctoral fellow at Stanford, and Basil O’Conner scholar, established Investigator of the American Heart Association, and Senior Investigator of Sandler’s Foundation for Asthma at UC San Diego. He received the MERCK award from the American Society of Biochemistry and Molecular Biology, is a fellow of the American association of the arts and science, and is an elected EMBO member.
- Expertise
- Biochemistry and Chemical Biology
- Cell Biology
- Research focus
- Golgi membranes
- protein secretion
- collagen
- mucins
- unconventional protein secretion
- Competing interests statement
- Vivek Malhotra receives funding from ERC/European Research Council, Ministerio de Economía y Competitividad, AGAUR and the Plan Nacional (Spain) He is a Scientific Advisory Board member of TIGEM (Naples, Italy), CNR (Naples, Italy), CBMSO (Madrid, Spain) and Department of Biotechnology (India). He has served on the editorial board of Cell and was an associate editor of Molecular Biology of the Cell. He is currently on the editorial boards of Journal of Cell Biology and Current Opinion in Cell Biology.
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Michael Marletta
University of California, Berkeley, United States
Michael Marletta holds the CH and Annie Li Chair in the Molecular Biology of Disease and is Professor of Chemistry and of Molecular and Cell Biology at the University of California, Berkeley. Previous to his appointment at UC Berkeley, he was a former President and CEO of The Scripps Research Institute. He has also been on the faculty of the University of Michigan, where he was an HHMI Investigator, and MIT. Marletta obtained an A.B. in chemistry and biology from the State University of New York at Fredonia, a PhD from UCSF under George Kenyon and, after a postdoctoral appointment at MIT under Chris Walsh, began his independent career at MIT. His work has spanned protein chemistry and enzymology. He has made many contributions to our understanding of nitric oxide signaling and more generally in molecular mechanisms of gas sensing in eukaryotes and prokaryotes. More recent studies have involved novel enzymes involved with cellulose degradation. Marletta is a member of the National Academy of Sciences, the National Academy of Medicine, the American Academy of Arts and Sciences and the American Philosophical Society.
- Expertise
- Biochemistry and Chemical Biology
- Research focus
- chemical biology
- nitric oxide signaling
- gas sensing
- structural basis of enzyme activity
- enzymology
- protein structure
- protein function
- metals in biology
- cell signaling
- Experimental organism
- E. coli
- human
- Competing interests statement
- Michael Marletta has received funding from the NIH, NSF, HHMI, and the Burroughs-Wellcome Fund. He is a member of the Biomedical Sciences Advisory Board at Vanderbilt University. He is a member of the Foundation Board at SUNY Fredonia. He is a co-founder of Omniox, Inc. He is a member of the Intelligence Community Studies Board of the National Academies.
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David Ron
Cambridge University, United Kingdom
David Ron is a Professor at Cambridge University. He directs a lab at the Cambridge Institute for Medical Research (CIMR) studying protein-folding homeostasis in the endoplasmic reticulum (ER). The lab uses biochemical, biophysical and cell-based tools to research both the molecular mechanisms that recognize the burden of unfolded proteins and thus initiate signalling in the ER unfolded protein response (UPR) and the downstream effector pathways by which cells adapt to unfolded protein stress in their ER. These effector mechanisms engage post-translational regulation of ER chaperone function, regulated translation of mRNA and transcriptional control of gene expression and thus interface with other cellular stress pathways.
To eLife, David Ron brings scientific expertise in the study of the unfolded protein response, chaperone function and stress-induced regulation of mRNA translation and editorial experience from having served as an eLife Reviewing Editor since 2012.
- Expertise
- Biochemistry and Chemical Biology
- Cell Biology
- Research focus
- chaperones
- unfolded protein response
- oxidative protein folding
- protein synthesis
- Experimental organism
- C. elegans
- E. coli
- human
- mouse
- S. cerevisiae
- Competing interests statement
- David Ron holds a Wellcome Trust Principal Research Fellowship and is on the editorial advisory boards of J. Cell Science, PLOS Biology and EMBO J.
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Cynthia Wolberger
Johns Hopkins University School of Medicine, United States
Cynthia Wolberger is a Professor of Biophysics and Biophysical Chemistry at the Johns Hopkins University School of Medicine, whose faculty she joined in 1991. She received her AB in Physics from Cornell University and her PhD in Biophysics from Harvard University, where she did thesis work on the structural basis of protein-DNA interactions under the guidance of Steve Harrison and Mark Ptashne. After a postdoctoral fellowship at the University of California, San Francisco with Bob Stroud, she worked on the crystal structures of homeodomain-DNA complexes in the laboratory of Carl Pabo at Johns Hopkins. Her earlier worked focused on the structural basis for combinatorial regulation of gene expression and the molecular mechanisms of the sirtuin family of protein deacetylases. Her current research centers on the mechanisms by which ubiquitin plays a signaling role in transcription and the DNA damage response. Wolberger was a recipient of the David and Lucile Packard Fellowship for Science and Engineering, a March of Dimes–Basil O’Conor Starter Scholar Award, and an American Cancer Society Junior Faculty Award, and was a Howard Hughes Medical Institute Investigator from 1994–2014. She received the Protein Society’s Dorothy Crowfoot Hodgkin Award and is a Fellow of the American Association for the Advancement of Science. Dr. Wolberger is a member of the National Academy of Sciences and the American Academy of Arts and Sciences.
- Expertise
- Structural Biology and Molecular Biophysics
- Chromosomes and Gene Expression
- Biochemistry and Chemical Biology
- Research focus
- ubiquitin
- chromatin
- transcription
- post-translational modifications
- histone-modifying enzymes
- Competing interests statement
- Cynthia Wolberger receives funding from the National Institutes of Health , the US–Israel Binational Science Foundation, and the Emerson Collective. She serves on the scientific advisory boards of Thermo Fisher Scientific and the Max Planck Institute for Biochemistry in Martinsried, Germany. She is a member of the Editorial Advisory Board of Protein Science, the Editorial Boards of Structure and Current Opinion in Structural Biology, and is a Faculty of 1000 section head in Transcription and Translation.
Reviewing editors
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Jonathan Abraham
Harvard Medical School, United States
- Expertise
- Biochemistry and Chemical Biology
- Structural Biology and Molecular Biophysics
- Microbiology and Infectious Disease
- Medicine
- Research focus
- emerging viruses
- antibody neutralisation
- viral entry
- viral replication
- x-ray crystallography
- cryo-EM
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James Berger
Johns Hopkins University School of Medicine, United States
- Expertise
- Biochemistry and Chemical Biology
- Structural Biology and Molecular Biophysics
- Research focus
- x-ray crystallography
- electron microscopy
- biochemistry
- biophysics
- DNA replication
- ATPase mechanism
- DNA topology
- topoisomerases
- helicases
- Experimental organism
- B. subtilis
- D. melanogaster
- E. coli
- human
- S. cerevisiae
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Douglas L Black
University of California, Los Angeles, United States
- Expertise
- Biochemistry and Chemical Biology
- Chromosomes and Gene Expression
- Research focus
- RNA splicing
- alternative splicing
- RNA binding proteins
- post-transcriptional gene regulation
- neuronal gene expression
- neuronal development
- polypyrimidine tract binding proteins
- Rbfox proteins
- Experimental organism
- mammalian cells
- mouse
- ES cell models
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Amie K Boal
Pennsylvania State University, United States
- Expertise
- Biochemistry and Chemical Biology
- Structural Biology and Molecular Biophysics
- Research focus
- bioinorganic chemistry
- enzymes
- microbial chemistry
- x-ray crystallography
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Michael R Botchan
University of California, Berkeley, United States
- Expertise
- Biochemistry and Chemical Biology
- Chromosomes and Gene Expression
- Research focus
- DNA replication
- DNA repair
- Experimental organism
- D. melanogaster
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Agnieszka Chacinska
University of Warsaw, Poland
- Expertise
- Biochemistry and Chemical Biology
- Cell Biology
- Research focus
- biogenesis
- organelles
- mitochondria
- protein transport
- proteasome
- protein degradation
- protein synthesis
- Experimental organism
- S. cerevisiae
- mammalian cells
- nematode
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Pimchai Chaiyen
Vidyasirimedhi Institute of Science and Technology (VISTEC), Thailand
- Expertise
- Biochemistry and Chemical Biology
- Research focus
- enzyme catalysis
- enzyme engineering
- systems biocatalysis
- metabolic engineering
- synthetic biology
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Jon Clardy
Harvard Medical School, United States
- Expertise
- Biochemistry and Chemical Biology
- Ecology
- Microbiology and Infectious Disease
- Research focus
- microbial secondary metabolism
- chemical communications
- biosynthesis
- chemical biology
- microbial chemical ecology
- gut microbiome
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Lydia Contreras
The University of Texas at Austin, United States
- Expertise
- Biochemistry and Chemical Biology
- Microbiology and Infectious Disease
- Research focus
- bacteria
- regulatory RNAs
- sRNAs
- bacterial regulation
- epitranscriptomics
- RNA modifications
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Ben Cravatt
Scripps Research Institute, United States
- Expertise
- Biochemistry and Chemical Biology
- Research focus
- chemical biology
- proteomics
- neurochemistry
- pharmacology
- Experimental organism
- human
- mouse
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Qiang Cui
Boston University, United States
- Expertise
- Biochemistry and Chemical Biology
- Structural Biology and Molecular Biophysics
- Research focus
- molecular dynamics
- hybrid quantum
- classical simulations
- enzyme catalysis
- allostery
- protein dynamics
- membrane remodeling
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Laura Dassama
Stanford University, United States
- Expertise
- Biochemistry and Chemical Biology
- Microbiology and Infectious Disease
- Research focus
- bacterial multidrug resistance
- chemoenzymatic syntheses
- beta-hemoglobinopathies
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Irwin Davidson
Institut de Genetique et de Biologie Moleculaire et Cellulaire, CNRS/INSERM/UDS, France
- Expertise
- Biochemistry and Chemical Biology
- Cancer Biology
- Chromosomes and Gene Expression
- Research focus
- transcription
- chromatin
- genomics
- cancer
- Experimental organism
- human
- mouse
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Lucie Delemotte
Science for Life Laboratory, Sweden
- Expertise
- Structural Biology and Molecular Biophysics
- Biochemistry and Chemical Biology
- Physics of Living Systems
- Research focus
- bioinformatics
- channelopathies
- computational biophysics
- free-energy calculations
- ion channels
- kinetic modeling
- molecular dynamics
- structure-function relationship
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Ivan Dikic
Goethe University Frankfurt, Germany
- Expertise
- Biochemistry and Chemical Biology
- Cell Biology
- Research focus
- ubiquitination
- autophagy
- bacterial effectors
- Legionella
- ER-phagy
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David Drew
University of Stockholm, Sweden
- Expertise
- Biochemistry and Chemical Biology
- Structural Biology and Molecular Biophysics
- Research focus
- membrane transporters
- x-ray crystallography
- cryo-EM
- membrane protein biotechnology
- bioenergetics
- solute carrier (SLC) transport
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Stephen C Ekker
Mayo Clinic, United States
- Expertise
- Developmental Biology
- Biochemistry and Chemical Biology
- Research focus
- gene editing
- morpholinos
- transposons
- mitochondria
- health engineering
- Experimental organism
- zebrafish
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Aaron Frank
University of Michigan, United States
- Expertise
- Structural Biology and Molecular Biophysics
- Biochemistry and Chemical Biology
- Research focus
- molecular modeling
- biophysics
- structural biology
- computation
- RNA biochemistry
- RNA structural biology
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Adam Frost
University of California, San Francisco, United States
- Expertise
- Structural Biology and Molecular Biophysics
- Biochemistry and Chemical Biology
- Cell Biology
- Research focus
- cryo-EM
- electron cryo-microscopy
- membranes
- membrane remodeling
- proteostasis
- stress responses
- translation
- mitochondria
- nuclear envelope
- intracellular trafficking
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Karine A Gibbs
Harvard University, United States
- Expertise
- Microbiology and Infectious Disease
- Biochemistry and Chemical Biology
- Research focus
- Proteus mirabilis
- sociomicrobiology
- bacterial genetics
- kin discrimination
- self/non-self recognition
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Ruben Gonzalez
Columbia University, United States
- Expertise
- Biochemistry and Chemical Biology
- Structural Biology and Molecular Biophysics
- Research focus
- translation
- translational control
- ribosomes
- RNA
- tRNA
- single-molecule biophysics
- single-molecule fluorescence resonance energy transfer
- cryo-EM
- biochemistry
- live cell imaging
- Experimental organism
- B. subtilis
- E. coli
- human
- S. cerevisiae
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Rachel Green
Johns Hopkins University School of Medicine, United States
- Expertise
- Biochemistry and Chemical Biology
- Chromosomes and Gene Expression
- Research focus
- ribosomes
- mechanisms of protein synthesis
- ribosome-mediated quality control
- mRNA degradation
- ribosome homeostasis/ribosomopathies
- stress responses
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Nikolaus Grigorieff
Janelia Research Campus, United States
- Expertise
- Biochemistry and Chemical Biology
- Structural Biology and Molecular Biophysics
- Research focus
- structural biology
- image processing
- biophysics
- electron microscopy
- cryo-EM
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Franz-Ulrich Hartl
Max Planck Institute of Biochemistry, Germany
- Expertise
- Biochemistry and Chemical Biology
- Structural Biology and Molecular Biophysics
- Research focus
- protein folding
- molecular chaperones
- neurodegenerative disorders
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Brandon Harvey
NIDA/NIH, Intramural Research Program, United States
- Expertise
- Biochemistry and Chemical Biology
- Cell Biology
- Chromosomes and Gene Expression
- Immunology and Inflammation
- Neuroscience
- Research focus
- ER stress
- ER calcium
- neuroinflammation
- gene therapy
- cellular neuroscience
- gene delivery
- Experimental organism
- rat
- mouse
- human cells
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Manajit Hayer-Hartl
Max Planck Institute of Biochemistry, Germany
- Expertise
- Biochemistry and Chemical Biology
- Structural Biology and Molecular Biophysics
- Research focus
- molecular chaperones
- protein folding and assembly
- protein misfolding and aggregation
- molecular machines
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Heedeok Hong
Michigan State University, United States
- Expertise
- Structural Biology and Molecular Biophysics
- Biochemistry and Chemical Biology
- Research focus
- membrane proteins
- membrane protein folding
- membrane protein stability
- rhomboid proteases
- ATP-dependent proteolysis
- AAA+
- GlpG
- FtsH
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Pankaj Kapahi
Buck Institute for Research on Aging, United States
- Expertise
- Biochemistry and Chemical Biology
- Developmental Biology
- Research focus
- aging
- age-related diseases
- nutrient signaling
- metabolism
- inflammation
- Experimental organism
- C. elegans
- D. melanogaster
- E. coli
- mouse
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Mary B Kennedy
California Institute of Technology, United States
- Expertise
- Biochemistry and Chemical Biology
- Computational and Systems Biology
- Neuroscience
- Research focus
- synaptic plasticity
- synaptic regulation
- biochemical signal transduction networks
- systems biology
- Experimental organism
- mouse
- rat
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Beno?t Kornmann
University of Oxford, United Kingdom
- Expertise
- Biochemistry and Chemical Biology
- Cell Biology
- Genetics and Genomics
- Research focus
- membrane contact sites
- mitochondria
- membrane dynamics
- membrane trafficking
- phospholipids
- Experimental organism
- S. cerevisiae
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David M Kramer
Michigan State University, United States
- Expertise
- Biochemistry and Chemical Biology
- Plant Biology
- Physics of Living Systems
- Structural Biology and Molecular Biophysics
- Research focus
- photosynthesis
- bioenergetics
- electron and proton transfer
- plant biology
- phenotyping
- Experimental organism
- A. thaliana
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Yamuna Krishnan
University of Chicago, United States
- Expertise
- Biochemistry and Chemical Biology
- Research focus
- nucleic acid-based molecular devices
- DNA machines
- chemical biology
- synthetic biology
- bioengineering
- Experimental organism
- C. elegans
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Andrew C Kruse
Harvard Medical School, United States
- Expertise
- Structural Biology and Molecular Biophysics
- Biochemistry and Chemical Biology
- Research focus
- signal transduction
- G protein-coupled receptors (GPCR)
- membrane proteins
- x-ray crystallography
- molecular pharmacology
- yeast surface display
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Karsten Kruse
University of Geneva, Switzerland
- Expertise
- Biochemistry and Chemical Biology
- Physics of Living Systems
- Research focus
- cell migration
- cell signalling
- theoretical biology
- molecular evolution
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Tatiana G Kutateladze
University of Colorado School of Medicine, United States
- Expertise
- Biochemistry and Chemical Biology
- Structural Biology and Molecular Biophysics
- Research focus
- NMR
- X-ray crystallography
- structure
- epigenetics
- Experimental organism
- human
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Ashish Lal
National Institutes of Health, United States
- Expertise
- Cancer Biology
- Biochemistry and Chemical Biology
- Chromosomes and Gene Expression
- Genetics and Genomics
- Research focus
- RNA biology
- lncRNAs
- microRNAs
- gene regulation
- cancer biology
- p53
- Experimental organism
- human
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Joanne Lemieux
University of Alberta, United States
- Expertise
- Biochemistry and Chemical Biology
- Structural Biology and Molecular Biophysics
- Research focus
- protease
- intramembrane protease
- crystallography
- membrane proteins
- structural biology
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Hening Lin
Cornell University, United States
- Expertise
- Biochemistry and Chemical Biology
- Cell Biology
- Research focus
- sirtuin
- PARP
- diphthamide
- post-translational modifications
- proteomics
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Sebastian Lourido
Whitehead Institute for Biomedical Research, United States
- Expertise
- Microbiology and Infectious Disease
- Cell Biology
- Genetics and Genomics
- Biochemistry and Chemical Biology
- Research focus
- calcium signaling
- host-pathogen interactions
- genetic screening
- protein kinases
- genomics
- quantitative proteomics
- Apicomplexan parasites
- Experimental organism
- T. gondii
- P. falciparum
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Andrei Lupas
Max Planck Institute for Developmental Biology, Germany
- Expertise
- Computational and Systems Biology
- Biochemistry and Chemical Biology
- Structural Biology and Molecular Biophysics
- Research focus
- bacterial surface proteins
- bioinformatics
- coiled coils
- protein design
- protein evolution
- protein structure
- transmembrane signal tranduction
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Merritt Maduke
Stanford University School of Medicine, United States
- Expertise
- Biochemistry and Chemical Biology
- Structural Biology and Molecular Biophysics
- Neuroscience
- Research focus
- chloride ion channels
- transporters
- electrophysiology
- structure-function
- membrane protein biophysics
- ultrasonic neuromodulation
- Experimental organism
- E. coli
- mouse
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Koyeli Mapa
Shiv Nadar University, India
- Expertise
- Biochemistry and Chemical Biology
- Research focus
- chaperones
- proteostasis
- protein folding
- mitochondria
- stress response
- Hsp70
- Hsp60
- unfolded protein response
- cell culture system
- Experimental organism
- S. cerevisiae
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Andreas Martin
University of California, Berkeley, United States
- Expertise
- Biochemistry and Chemical Biology
- Structural Biology and Molecular Biophysics
- Research focus
- AAA+ ATPases
- protein degradation
- proteostasis
- ATPase mechanism
- protein folding
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Malcolm J McConville
University of Melbourne, Australia
- Expertise
- Microbiology and Infectious Disease
- Biochemistry and Chemical Biology
- Research focus
- protozoan parasites
- metabolomics
- metabolism
- Leishmaniasis
- trypanosomatids
- glycobiology
- Experimental organism
- T. gondii
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Elizabeth A Miller
MRC Laboratory of Molecular Biology, United Kingdom
- Expertise
- Cell Biology
- Biochemistry and Chemical Biology
- Research focus
- membrane traffic
- endoplasmic reticulum
- protein quality control
- COPII vesicles
- Experimental organism
- S. cerevisiae
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Noboru Mizushima
University of Tokyo, Japan
- Expertise
- Biochemistry and Chemical Biology
- Cell Biology
- Research focus
- protein degradation
- lysosome
- autophagy
- protein/organelle degradation
- autophagosome
- Experimental organism
- mouse
- yeast
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Binyam Mogessie
University of Bristol, United Kingdom
- Expertise
- Biochemistry and Chemical Biology
- Cell Biology
- Research focus
- meiosis
- mitosis
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Hitoshi Nakatogawa
Tokyo Institute of Technology, Japan
- Expertise
- Cell Biology
- Biochemistry and Chemical Biology
- Research focus
- molecular mechanisms of autophagy
- protein/organelle degradation
- membrane dynamics
- Experimental organism
- S. cerevisiae
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Geeta Narlikar
University of California, San Francisco, United States
- Expertise
- Biochemistry and Chemical Biology
- Structural Biology and Molecular Biophysics
- Research focus
- chromatin
- heterochromatin spread
- chromatin remodeling machines
- phase-separation
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Hannes Neuweiler
University of Würzburg, Germany
- Expertise
- Structural Biology and Molecular Biophysics
- Biochemistry and Chemical Biology
- Research focus
- protein dynamics
- protein folding
- protein engineering
- fluorescence spectroscopy
- fluorescence probe development
- single-molecule fluorescence spectroscopy
- kinetics
- Experimental organism
- E. coli
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Timothy Nilsen
Case Western Reserve University, United States
- Expertise
- Biochemistry and Chemical Biology
- Chromosomes and Gene Expression
- Research focus
- mRNA processing
- mechanism of miRNA function
- RNA protein interactions
- mRNP composition and function
- RNA biology
- Experimental organism
- D. melanogaster
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Kim Orth
University of Texas Southwestern Medical Center, United States
- Expertise
- Biochemistry and Chemical Biology
- Microbiology and Infectious Disease
- Research focus
- bacterial pathogenesis
- Type III secretion
- host-pathogen interactions
- signaling
- AMPylation
- Experimental organism
- Vibrio spp
- E. coli
- human
- S. cerevisiae
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Jon Pines
Institute of Cancer Research, University College London, United Kingdom
- Expertise
- Biochemistry and Chemical Biology
- Cell Biology
- Research focus
- cyclins and anaphase promoting complex/cycosome (APC/C)
- cell cycle
- mitosis
- spindle assembly checkpoint
- Experimental organism
- human
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Stephan Pless
University of Copenhagen, Denmark
- Expertise
- Structural Biology and Molecular Biophysics
- Biochemistry and Chemical Biology
- Research focus
- ion channels
- pharmacology
- electrophysiology
- biophysics
- chemical biology
- non-canonical amino acids
- protein engineering
- neurobiology
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Arun Radhakrishnan
University of Texas Southwestern Medical Center, United States
- Expertise
- Biochemistry and Chemical Biology
- Cell Biology
- Structural Biology and Molecular Biophysics
- Research focus
- lipid sensors
- cholesterol
- sphingomyelin
- cholesterol transport
- SREBP
- Scap
- cholesterol homeostasis
- endoplasmic reticulum
- Experimental organism
- E. coli
- human
- mouse
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Michael Rape
University of California, Berkeley, United States
- Expertise
- Biochemistry and Chemical Biology
- Cell Biology
- Research focus
- stem cells
- ubiquitin
- ubiquitylation
- degradation
- proteasome
- E3 ligase
- p97/VCP
- differentiation
- quality control
- Experimental organism
- human
- mouse
- Xenopus
-
Janice L Robertson
Washington University in St. Louis, United States
- Expertise
- Structural Biology and Molecular Biophysics
- Computational and Systems Biology
- Physics of Living Systems
- Biochemistry and Chemical Biology
- Research focus
- membrane protein folding
- computational modeling
- oligomerization
- membrane transport
- driving forces
- lipids
-
Rajan Sankaranarayanan
CSIR – Centre for Cellular and Molecular Biology, India
- Expertise
- Biochemistry and Chemical Biology
- Structural Biology and Molecular Biophysics
- Research focus
- translation quality control
- proofreading
- structural biology
- x-ray crystallography
- enzyme mechanisms
- Experimental organism
- E. coli
-
Tricia Serio
The University of Massachusetts, Amherst, United States
- Expertise
- Biochemistry and Chemical Biology
- Cell Biology
- Research focus
- prion
- protein misfolding
- chaperones
- amyloid
- Experimental organism
- S. cerevisiae
-
Nima Sharifi
Cleveland Clinic, United States
- Expertise
- Biochemistry and Chemical Biology
- Cancer Biology
- Medicine
- Research focus
- steroid biochemistry
- steroid metabolism
- prostate cancer
- nuclear receptors
- hormone therapy resistance
- androgens
- oncology
- Experimental organism
- mouse
-
Akira Shinohara
Osaka University, Japan
- Expertise
- Biochemistry and Chemical Biology
- Chromosomes and Gene Expression
- Cell Biology
- Research focus
- recombination
- DSB repair
- meiosis
- chromosome
- DNA damage response
- Experimental organism
- S. cerevisiae
- human
- mouse
-
Gustavo Monteiro Silva
Duke University, United States
- Expertise
- Biochemistry and Chemical Biology
- Research focus
- ubiquitin
- oxidative stress
- translation
- proteomics
- Experimental organism
- human
- mouse
- S. cerevisiae
-
Randy B Stockbridge
University of Michigan, United States
- Expertise
- Biochemistry and Chemical Biology
- Structural Biology and Molecular Biophysics
- Research focus
- ion channels
- transporters
- microbial membrane proteins
- crystallography
- electrophysiology
- Experimental organism
- E. coli
-
Wesley Sundquist
University of Utah School of Medicine, United States
- Expertise
- Structural Biology and Molecular Biophysics
- Microbiology and Infectious Disease
- Biochemistry and Chemical Biology
- Research focus
- virus assembly
- HIV
- ESCRT
- abscission
- innate immunity
-
Eric J Wagner
University of Texas Medical Branch at Galveston, United States
- Expertise
- Chromosomes and Gene Expression
- Biochemistry and Chemical Biology
- Cancer Biology
- Genetics and Genomics
- Research focus
- RNA biology
- transcription
- RNA processing
- gene expression
-
Oliver Weichenrieder
Max Planck Institute for Developmental Biology, Germany
- Expertise
- Biochemistry and Chemical Biology
- Structural Biology and Molecular Biophysics
- Genetics and Genomics
- Research focus
- retrotransposition
- regulatory mRNA
- x-ray crystallography
- structural biology
-
William I Weis
Stanford University, United States
- Expertise
- Biochemistry and Chemical Biology
- Structural Biology and Molecular Biophysics
- Research focus
- cell adhesion
- wnt signaling
- x-ray crystallography
- structural biology
- Experimental organism
- C. elegans
- Dictyostelium
- human
- mouse
-
Ahmet Yildiz
University of California, Berkeley, United States
- Expertise
- Structural Biology and Molecular Biophysics
- Biochemistry and Chemical Biology
- Physics of Living Systems
- Research focus
- dynein
- kinesin
- microtubules
- intraflagellar transport
- single molecule-biophysics
- shelterin
- telomeres
- Experimental organism
- E. coli
- human
- S. cerevisiae
-
Mingjie Zhang
Hong Kong University of Science and Technology, Hong Kong SAR China
- Expertise
- Biochemistry and Chemical Biology
- Structural Biology and Molecular Biophysics
- Research focus
- postsynaptic density
- synaptic signaling
- scaffold proteins
- liquid-liquid phase separation
- biological condensates